Anti-TUT1 antibody produced in rabbit
SIGMA/SAB2102610 - affinity isolated antibody
Synonym: Anti-FLJ21850; Anti-FLJ22267; Anti-FLJ22347; Anti-MGC131987; Anti-Terminal uridylyl transferase 1, U6 snRNA-specific
Product Type: Chemical
Immunoblotting Anti-TUT1: Cat. No.SAB2102610: TUT1 in 293T cell lysate with TUT1 antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 94 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | guinea pig, bovine, human, horse, dog |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q9H6E5  |
| Biochem/physiol Actions: | TUT1 is a nucleotidyl transferase that functions as both a terminal uridylyltransferase and a nuclear poly(A) polymerase. TUT1 specifically adds and removes nucleotides from the 3′ end of small nuclear RNAs and select mRNAs and may function in controlling gene expression and cell proliferation.TUT1 specifically catalyzes uridylylation of U6 snRNA (RNU6; MIM 180692) and is essential for cell proliferation (Trippe et al., 2006 [PubMed 16790842]).[supplied by OMIM]. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | The previously assigned protein identifier A8K995 has been merged into Q9H6E5. Full details can be found on the UniProt database. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human TUT1 |
| Other Notes: | Synthetic peptide located within the following region: CDLDLFLDLGDLEEPQPVPKAPESP |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |