Anti-UBE2D3 antibody produced in rabbit
SIGMA/SAB2102622 - affinity isolated antibody
Synonym: Anti-E2(17)KB3; Anti-MGC43926; Anti-MGC5416; Anti-UBC4/5; Anti-
Product Type: Chemical
Immunoblotting Anti-UBE2D3: Cat. No.SAB2102622: UBE2D3 in MCF7 cell lysate with UBE2D3 antibody at 1.0 μg/mL.
Western Blotting Western Blot of UBE2D3 in Recombinant protein with UBE2D3 antibody at 1 μg/mL
Western Blotting Western Blot of UBE2D3 in Human Jurkat with UBE2D3 antibody at 1 μg/mL
Western Blotting Western Blot of UBE2D3 in Human MCF7 with UBE2D3 antibody at 1 μg/mL
Western Blotting Western Blot of UBE2D3 in Human Fetal Lung with UBE2D3 antibody at 1 μg/mL
Western Blotting Western Blot of UBE2D3 in Human Fetal Liver with UBE2D3 antibody at 1 μg/mL
Western Blotting Western Blot of UBE2D3 in Human HEK293T with UBE2D3 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 17 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | rat, bovine, guinea pig, dog, human, horse, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | P61077  |
| Biochem/physiol Actions: | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human UBE2D3 |
| Other Notes: | Synthetic peptide located within the following region: MALKRINKELSDLARDPPAQCSAGP |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |