Anti-UBQLN1 antibody produced in rabbit
SIGMA/SAB2102632 - affinity isolated antibody
Synonym: Anti-DA41; Anti-DSK2; Anti-FLJ90054; Anti-PLIC-1; Anti-Ubiquilin 1
Product Type: Chemical
Immunohistochemistry Anti-UBQLN1: Cat. No. SAB2102632: Immunohistochemistry of UBQLN1 in Human Lung, respiRatory epethelium tissue with UBQLN1 antibody at 5.0 μg/mL.
Immunohistochemistry Immunohistochemistry of UBQLN1 in human brain, cortex with UBQLN1 antibody at 4-8 μg/mL
Immunohistochemistry Immunohistochemistry of UBQLN1 in human prostate with UBQLN1 antibody at 4-8 μg/mL
Immunoblotting Anti-UBQLN1: Cat. No.SAB2102632: UBQLN1 in 293T cell lysate with UBQLN1 antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 62 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | guinea pig, rat, human, dog, bovine, horse, rabbit, sheep |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q9UMX0  |
| Biochem/physiol Actions: | UBQLN1 is an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer′s and Parkinson′s disease. Two transcript variants encoding different isoforms have been found for this gene.This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with Alzheimer′s and Parkinson′s disease. Two transcript variants encoding different isoforms have been found for this gene. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | The previously assigned protein identifier Q5T6J9 has been merged into Q9UMX0. Full details can be found on the UniProt database. |
| Immunogen: | Synthetic peptide directed towards the middle region of human UBQLN1 |
| Other Notes: | Synthetic peptide located within the following region: QFGGNPFASLVSNTSSGEGSQPSRT |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |