Anti-MSX2, (N-terminal) antibody produced in rabbit
SIGMA/SAB2103331 - affinity isolated antibody
Synonym: Anti-CRS2; Anti-FPP; Anti-HOX8; Anti-MSH; Anti-PFM
MDL Number: MFCD01633881
Product Type: Chemical
Immunofluorescence Immunofluorescence of MSX2 in MCF7 with MSX2 antibody at 4-8 μg/mL
Immunoblotting Anti-MSX2, antibody produced in rabbit: Cat. No. SAB2103331: Immunoblotting analysis of MSX2 in transfected 293T cell lysate with MSX2 anitbody at 1 μg/mL.
Western Blotting Western Blot of MSX2 in Mouse Pancreas with MSX2 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 29 kDa |
| NCBI accession no. | NM_002449   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | bovine, horse, dog, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunofluorescence: suitable |
| western blot: suitable | |
| UniProt accession no. | P35548 |
| Biochem/physiol Actions: | MSX2 probable play a morphogenetic role. MSX2 may play a role in limb-pattern formation. In osteoblasts, MSX2 suppresses transcription driven by the osteocalcin FGF response element (OCFRE).This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the n terminal region of human MSX2 |
| Other Notes: | Synthetic peptide located within the following region: MASPSKGNDLFSPDEEGPAVVAGPG |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |