Anti-SP3 antibody produced in rabbit
SIGMA/SAB2103396 - affinity isolated antibody
Synonym: Anti-DKFZp686O1631; Anti-SPR-2
Product Type: Chemical
Immunohistochemistry Anti-SP3: Cat. No. SAB2103396: Immunohistochemistry of SP3 in Human Prostate tissue with SP3 antibody at 5.0 μg/mL.
Immunoblotting Anti-SP3, antibody produced in rabbit: Cat. No. SAB2103396: Immunoblotting analysis of SP3 in fetal muscle tissue lysate with SP3 anitbody at 1 μg/mL.
Western Blotting Western Blot of SP3 in Human U2OS with SP3 antibody at 1 μg/mL
Western Blotting Western Blot of SP3 in Mouse Skeletal Muscle with SP3 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 82 kDa |
| NCBI accession no. | NM_003111   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, dog, bovine, mouse, guinea pig, rabbit, rat, horse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q02447 |
| Biochem/physiol Actions: | SP3 is a transcriptional factor that can act as an activator or repressor, probably in a isoform-specific manner. SP3 binds to GT and GC boxes promoters elements.This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human SP3 |
| Other Notes: | Synthetic peptide located within the following region: TAGINADGHLINTGQAMDSSDNSER |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |