Anti-SIAH2 antibody produced in rabbit
SIGMA/SAB2103404 - affinity isolated antibody
Synonym: Anti-hSiah2
Product Type: Chemical
Immunoblotting Anti-SIAH2, antibody produced in rabbit: Cat. No. SAB2103404: Immunoblotting analysis of SIAH2 in fetal muscle tissue lysate with SIAH2 anitbody at 1 μg/mL.
Western Blotting Western Blot of SIAH2 in Human 721_B with SIAH2 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 34 kDa |
| NCBI accession no. | NM_005067   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | guinea pig, rat, mouse, human, dog, rabbit, horse, bovine |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | O43255 |
| Biochem/physiol Actions: | SIAH2 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia.This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human SIAH2 |
| Other Notes: | Synthetic peptide located within the following region: AVDWVMMQSCFGHHFMLVLEKQEKY |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |