Anti-MARCH5, (N-terminal) antibody produced in rabbit
SIGMA/SAB2103803 - affinity isolated antibody
Synonym: Anti-FLJ20445; Anti-MARCH-V; Anti-MITOL; Anti-RNF153
Product Type: Chemical
Immunoblotting Anti-40242, antibody produced in rabbit: Cat. No. SAB2103803: Immunoblotting analysis of MARCH5 in COLO205 cell lysate with MARCH5 anitbody at 1 μg/mL.
Immunoblotting MARCH5 Antibody: Cat. No. SAB2103803: Western Blot analysis of MARCH5 in U937 Whole cell lysates with MARCH5 Antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 31 kDa |
| NCBI accession no. | NM_017824   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, rat, bovine, dog, rabbit, horse, guinea pig, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q9NX47 |
| Biochem/physiol Actions: | MARCH5 is an ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2) and DRP1 (DNM1L). MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2; MIM 608507) and DRP1 (DNM1L; MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1502 AK000452.1 3-1504 1503-1863 BC015480.1 1463-1823 1864-1901 BE393612.1 438-475 1902-3713 BC015480.1 1852-3663 3714-3941 BC015480.1 3669-3896 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human MARCH5 |
| Other Notes: | Synthetic peptide located within the following region: CRGSTKWVHQACLQRWVDEKQRGNS |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |