Anti-NKX2-2, (N-terminal) antibody produced in rabbit
SIGMA/SAB2103965 - affinity isolated antibody
Synonym: Anti-NKX2B
Product Type: Chemical
Immunohistochemistry Anti-NKX2-2, (N-terminal): Cat. No. SAB2103965: Immunohistochemistry of NKX2-2 in Human optic nerve and spinal cord tissue with NKX2-2 antibody at 1-10 μg/mL.
Immunoblotting Anti-NKX2-2, antibody produced in rabbit: Cat. No. SAB2103965: Immunoblotting analysis of NKX2-2 in fetal spleen tissue lysate with NKX2-2 anitbody at 1 μg/mL.
Western Blotting Western Blot of NKX2-2 in Mouse Pancreas with NKX2-2 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 30 kDa |
| NCBI accession no. | NM_002509   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | sheep, bovine, dog, rat, horse, guinea pig, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | O95096 |
| Biochem/physiol Actions: | Nkx2-2 contains 1 homeobox DNA-binding domain which is essential for interaction with OLIG2. Nkx2-2 may be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human NKX2-2 |
| Other Notes: | Synthetic peptide located within the following region: MSLTNTKTGFSVKDILDLPDTNDEE |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |