Anti-ASCL2 antibody produced in rabbit
SIGMA/SAB2104130 - affinity isolated antibody
Synonym: Anti-ASH2; Anti-HASH2; Anti-MASH2
MDL Number: MFCD07370257
Product Type: Chemical
Immunoblotting Anti-ASCL2, antibody produced in rabbit: Cat. No. SAB2104130: Immunoblotting analysis of ASCL2 in DU145 cell lysate with ASCL2 anitbody at 1 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 20 kDa |
| NCBI accession no. | NM_005170   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, rat, bovine, dog, guinea pig |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q99929 |
| Biochem/physiol Actions: | Achaete scute-like 2 (Ascl2) is a downstream target of WNT signalling. It may act as a regulatory factor, which regulates the fate of colon cancer cells. Ascl2 is also accountable for the differentiation of the trophoblast lineage in normal placenta. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Achaete scute-like 2 (Ascl2) is a basic helix-loop-helix transcription factor. The base of small and large intestinal crypts and the placenta shows its expression. This gene is mapped to human chromosome 11p15. |
| Immunogen: | Synthetic peptide directed towards the middle region of human ASCL2 |
| Other Notes: | Synthetic peptide located within the following region: QALRQHVPHGGASKKLSKVETLRSA |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |