Anti-ETV1 antibody produced in rabbit
SIGMA/SAB2104467 - affinity isolated antibody
Synonym: Anti-DKFZp781L0674; Anti-ER81; Anti-MGC104699; Anti-MGC120533; Anti-MGC120534
Product Type: Chemical
Immunohistochemistry Anti-ETV1: Cat. No. SAB2104467: Immunohistochemistry of ETV1 in Brain, cortex tissue with ETV1 antibody at 4-8 μg/mL.
Immunoblotting Anti-ETV1, antibody produced in rabbit: Cat. No. SAB2104467: Immunoblotting analysis of ETV1 in HT1080 cell lysate with ETV1 anitbody at 1 μg/mL.
Western Blotting Western Blot of ETV1 in HEK293 with ETV1 antibody at 1 μg/mL
Western Blotting Western Blot of ETV1 in Human MDA-MB-435s with ETV1 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 55 kDa |
| NCBI accession no. | NM_004956   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | dog, horse, mouse, guinea pig, human, rat, bovine |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P50549 |
| Application: | Anti-ETV1 antibody produced in rabbit has been used in western blot(1:500) |
| Biochem/physiol Actions: | E-twenty-six (ETS) proteins participate in cell proliferation and cancer cell invasion. Ets variant gene 1 (ETV1) acts as a neuregulin-1 (NRG1) responsive factor and is important for establishing rapid conduction physiology in the heart. Overexpression of the gene has been observed in various types of cancers including prostate cancer and gastrointestinal stromal tumors |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Ets variant gene 1 (ETV1) is a novel androgen-regulated gene mapped to human chromosome 7p21.2. ETV1 protein belongs to the E-twenty-six (ETS) transcription factor family and it contains the ETS domain and acidic transactivation domain. ETV1 binds to DNA sequences containing the consensus pentanucleotide 5′-CGGA[AT]-3′. |
| Immunogen: | Synthetic peptide directed towards the middle region of human ETV1 |
| Other Notes: | Synthetic peptide located within the following region: PDNQRPLLKTDMERHINEEDTVPLS |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |