Anti-PDX1 antibody produced in rabbit
SIGMA/SAB2106245 - affinity isolated antibody
Product Type: Chemical
Immunoblotting Anti-PDX1: Cat. No. SAB2106245: Western blot analysis of Pdx1 in Mouse Pancreas with Pdx1 (pancreatic and duodenal homeobox 1) antibody against the N terminal of Pdx1 (50 μg) antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 31 kDa |
| NCBI accession no. | NM_008814   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rat, human, dog, rabbit, bovine, mouse, horse |
| storage temp. | −20°C |
| technique(s) | western blot: suitable |
| UniProt accession no. | P52946 |
| Biochem/physiol Actions: | Pdx1 activates insulin and somatostatin gene transcription. It is a key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. It binds the DNA sequence 5′-CC[CT]TAATGGG-3′. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | The immunogen for anti-PDX1 antibody: synthetic peptide derected towards the N terminal of human PDX1 |
| Other Notes: | Synthetic peptide located within the following region: LYMGRQPPPPPPPQFTSSLGSLEQG |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |