Anti-SIX1 antibody produced in rabbit
SIGMA/SAB2106448 - affinity isolated antibody
Product Type: Chemical
Immunohistochemistry SIX1 Antibody: Cat. No. SAB2106448: Immunohistochemistry analysis of SIX1 in heart with SIX1 Antibody 1.0 μg/mL. Observed Staining: Cytoplasmic,Nuclear (very rare in Nuclear)
Immunoblotting Anti-SIX1: Cat. No. SAB2106448: Western blot analysis of Six1 in Mouse Kidney with Six1 (sine oculis-related homeobox 1 homolog, Drosophila) antibody, against the N terminal of Six1 (50 μg) antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 32 kDa |
| NCBI accession no. | NM_009189   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, guinea pig, rat, dog, horse, mouse, bovine, sheep, rabbit |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q62231 |
| Biochem/physiol Actions: | Sine oculis homeobox homolog 1 (SIX1) enhances the rate of proliferation of cells and their survival. It has a role in organogenesis and has been linked to several malignancies. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Sine oculis homeobox homolog 1 (SIX1) is a transcription factor, having a homeodomain. It is part of the homeoprotein family and is expressed during embryogenesis. The gene encoding this protein is localized on human chromosome 14q23.1. |
| Immunogen: | The immunogen for anti-SIX1 antibody: synthetic peptide derected towards the N terminal of human SIX1 |
| Other Notes: | Synthetic peptide located within the following region: ERLGRFLWSLPACDHLHKNESVLKA |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |