Anti-NUDT16L1 antibody produced in rabbit
SIGMA/SAB2106808 - affinity isolated antibody
Synonym: TIRR; Tudor Interacting Repair Regulator
Product Type: Chemical
Immunoblotting Anti-NUDT16L1: Cat. No. SAB2106808: Western blot analysis of NUDT16L1 with NUDT16L1 (nudix, nucleoside diphosphate linked moiety X)-type motif 16-like 1) antibody against the middle region of NUDT16L1 (50 μg) antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 23 kDa |
| NCBI accession no. | NM_032349   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, dog, rat, human, bovine, guinea pig, rabbit |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q9BRJ7 |
| Biochem/physiol Actions: | Nudix hydrolase 16 like 1 (NUDT16L1) repairs double strand breaks by masking the histone methyl-lysine binding function of P53 binding protein 1 (53BP1). NUDT16L1 acts as an inhibitor of 53BP1. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Nudix hydrolase 16 like 1 (NUDT16L1) protein belongs to a nucleoside diphosphate-linked moiety X (Nudix) hydrolases family. It is also known as TIRR (tudor interacting repair regulator), which specifically interacts with the ionizing radiation induced foci formation (IRIF) region of P53 binding protein 1 (53BP1). NUDT16L1 gene is located on human chromosome 16p13.3. |
| Immunogen: | Synthetic peptide directed towards the middle region of human NUDT16L1 |
| Other Notes: | Synthetic peptide located within the following region: LNRVLGLGLGCLRLTEADYLSSHLT |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |