Anti-SNX10 antibody produced in rabbit
SIGMA/SAB2107086 - affinity isolated antibody
Product Type: Chemical
Immunoblotting Anti-SNX10: Cat. No. SAB2107086: Western blot analysis of Snx10 in Mouse Heart with Snx10 (sorting nexin 10) antibody against the middle region of Snx10 (50 μg) antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 22 kDa |
| NCBI accession no. | NM_001127348   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rat, human, mouse, bovine, pig, horse, rabbit |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q9CWT3 |
| Biochem/physiol Actions: | Snx10 may be involved in several stages of intracellular trafficking. May play a role in endosome homeostasis. Overexpression causes formation of huge vacuoles. Mutations in SNX10 leads to autosomal recessive osteoporosis due to dysregulation of osteoclasts. SNX10 interaction with vacuolar-type H+ -ATPase (V-ATPase) complex initiates ciliogenesis, critical for early embryonic development. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Sorting nexin 10 (SNX10) is a transmembrane protein belonging to SNX family. SNX10 has phox domain which binds to phosphoinositide-binding domain. In human chromosome, the gene SNX10 is located on 7p15.2. |
| Immunogen: | The immunogen for anti-SNX10 antibody: synthetic peptide derected towards the middle region of human SNX10 |
| Other Notes: | Synthetic peptide located within the following region: DFLRKVLQNALLLSDSSLHLFLQSH |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |