Anti-POU1F1 antibody produced in rabbit
SIGMA/SAB2107871 - affinity isolated antibody
Product Type: Product-on-demand
Immunohistochemistry Anti-POU1F1 (ab1): Cat. No. SAB2107871: Immunohistochemistry of POU1F1 in Human Liver tissue with POU1F1 antibody at 4-8 μg/mL.
Immunoblotting Cell Type: HepG2 (Cat. No. SAB2107871). Lanes 1. Antibody dilution (concentration) 1.0-10.0 μg/mL in cell type HepG2
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 33kDa |
| NCBI accession no. | NM_000306   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | sheep, bovine, guinea pig, dog, mouse, human, rabbit, horse, goat, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoblotting: suitable |
| immunohistochemistry: suitable | |
| UniProt accession no. | P28069 |
| Biochem/physiol Actions: | PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human POU1F1 |
| Other Notes: | Synthetic peptide located within the following region: QEIMRMAEELNLEKEVVRVWFCNRR |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |