Anti-SMARCB1 antibody produced in rabbit
SIGMA/SAB2107910 - affinity isolated antibody
Product Type: Product-on-demand
Immunohistochemistry Anti-SMARCB1 (ab1): Cat. No. SAB2107910: Immunohistochemistry of SMARCB1 in Human Liver tissue with SMARCB1 antibody at 4-8 μg/mL.
Immunohistochemistry SMARCB1 Antibody: Cat. No. SAB2107910: Immunohistochemistry analysis of SMARCB1 in Human Lung with SMARCB1 Antibody Antibody Concentration: 4.0-8.0 μg/mL. Cellular Data: Epithelial cells of renal tubule
Immunoblotting Cell Type: fetal thymus (Cat. No. SAB2107910). Lanes 1. Antibody dilution (concentration) 2.0 μg/mL in cell type fetal thymus
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 44kDa |
| NCBI accession no. | NM_003073   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, horse, mouse, bovine, dog, guinea pig, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoblotting: suitable |
| immunohistochemistry: suitable | |
| UniProt accession no. | Q12824 |
| Biochem/physiol Actions: | The protein encoded by SMARCB1 is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. SMARCB1 has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human SMARCB1 |
| Other Notes: | Synthetic peptide located within the following region: RGSLYKRYPSLWRRLATVEERKKIV |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |