Anti-FOXO3 antibody produced in rabbit
SIGMA/SAB2107951 - affinity isolated antibody
Product Type: Product-on-demand
Immunohistochemistry Immunohistochemistry of FOXO3 in Human Ovary with FOXO3 antibody at 4-8 μg/mL
Immunoblotting Cell Type: transfected 293T (Cat. No. SAB2107951). Lanes 1. Antibody dilution (concentration) 1 μg/mL in cell type transfected 293T
Western Blotting Western Blot of FOXO3 in Human Fetal Heart with FOXO3 antibody at 1 μg/mL
Western Blotting Western Blot of FOXO3 in Human Fetal Lung with FOXO3 antibody at 1 μg/mL
Western Blotting Western Blot of FOXO3 in Human Fetal Liver with FOXO3 antibody at 1 μg/mL
Western Blotting Western Blot of FOXO3 in Human Adult Placenta with FOXO3 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 71kDa |
| NCBI accession no. | NM_001455   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, pig, rat, human, dog, bovine, rabbit, sheep |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoblotting: suitable |
| UniProt accession no. | O43524 |
| Biochem/physiol Actions: | FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia.This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human FOXO3 |
| Other Notes: | Synthetic peptide located within the following region: MAEAPASPAPLSPLEVELDPEFEPQ |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |