Anti-FADS1 antibody produced in rabbit
SIGMA/SAB2108009 - IgG fraction of antiserum
Product Type: Product-on-demand
Immunohistochemistry Anti-FADS1: Cat. No. SAB2108009: Immunohistochemistry of FADS1 in Human Muscle tissue with FADS1 antibody at 4-8 μg/mL.
Immunoblotting Cell Type: K562 (Cat. No. SAB2108009). Lanes 1. Antibody dilution (concentration) 2.5 μg/mL in cell type K562
Western Blotting Western Blot of FADS1 in Human Fetal Liver with FADS1 antibody at 1 μg/mL
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 49kDa |
| NCBI accession no. | NM_013402   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rabbit, pig, mouse, horse, dog, bovine, human, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoblotting: suitable |
| immunohistochemistry: suitable | |
| UniProt accession no. | O60427 |
| Biochem/physiol Actions: | FADS1 is a member of the fatty acid desaturase (FADS) family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs.The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human FADS1 |
| Other Notes: | Synthetic peptide located within the following region: FNDWFSGHLNFQIEHHLFPTMPRHN |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |