Anti-IHH antibody produced in rabbit
SIGMA/SAB2108031 - IgG fraction of antiserum
Product Type: Product-on-demand
Immunohistochemistry Anti-IHH: Cat. No. SAB2108031: Immunohistochemistry of IHH in Human Kidney tissue with IHH antibody at 4-8 μg/mL.
Immunoblotting Cell Type: HepG2 (Cat. No. SAB2108031). Lanes 1. Antibody dilution (concentration) 1.25 μg/mL in cell type HepG2
Western Blotting Western Blot of IHH in Mouse Heart with IHH antibody at 1 μg/mL
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 45kDa |
| NCBI accession no. | NM_002181   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse, rabbit, guinea pig, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoblotting: suitable |
| immunohistochemistry: suitable | |
| UniProt accession no. | Q14623 |
| Biochem/physiol Actions: | IHH is an intercellular signal essential for a variety of patterning events during development. It binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. It is implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones and induces the expression of parathyroid hormone-related protein (PTHRP). |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human IHH |
| Other Notes: | Synthetic peptide located within the following region: AAWGCGPGRVVGSRRRPPRKLVPLA |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |