Anti-CPT1A antibody produced in rabbit
SIGMA/SAB2108104 - affinity isolated antibody
Product Type: Product-on-demand
Immunohistochemistry Immunohistochemistry of CPT1A in Human Capan1 with CPT1A antibody at 4-8 μg/mL
Immunoblotting Anti-CPT1A: Cat. No.SAB2108104: CPT1A in 293T cell lysate with CPT1A antibody at 1.0 μg/mL.
Western Blotting Western Blot of CPT1A in Human capan1, HPAF with CPT1A antibody at 1 μg/mL
Western Blotting Western Blot of CPT1A in 293T with CPT1A antibody at 1 μg/mL
Western Blotting Western Blot of CPT1A in Human HT1080 Whole Cell with CPT1A antibody at 1 μg/mL
Western Blotting Western Blot of CPT1A in Human MDA-MB-435s Whole Cell with CPT1A antibody at 1 μg/mL
Western Blotting Western Blot of CPT1A in Human Stomach Tumor with CPT1A antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 86kDa |
| NCBI accession no. | NM_001031847   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | horse, rat, sheep, bovine, mouse, dog, rabbit, guinea pig, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoblotting: suitable |
| immunohistochemistry: suitable | |
| UniProt accession no. | P50416 |
| Biochem/physiol Actions: | The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation.The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human CPT1A |
| Other Notes: | Synthetic peptide located within the following region: LSTSQTPQQQVELFDLENNPEYVSS |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |