Anti-FGF2 antibody produced in rabbit
SIGMA/SAB2108135 - affinity isolated antibody
Product Type: Product-on-demand
Immunohistochemistry Immunohistochemistry of FGF2 in Human A375 with FGF2 antibody at 4-8 μg/mL
Immunohistochemistry Immunohistochemistry of FGF2 in Human Ovary with FGF2 antibody at 4-8 μg/mL
Immunoblotting Anti-FGF2: Cat. No.SAB2108135: FGF2 in Jurkat cell lysate with FGF2 antibody at 1.0 μg/mL.
Western Blotting Western Blot of FGF2 in Human HeLa with FGF2 antibody at 1 μg/mL
Western Blotting Western Blot of FGF2 in Human Lung Tumor with FGF2 antibody at 1 μg/mL
Western Blotting Western Blot of FGF2 in Mouse Skeletal Muscle with FGF2 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| application(s) | research pathology |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 31kDa |
| NCBI accession no. | NM_002006   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, human, guinea pig, rat, rabbit |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoblotting: suitable |
| immunohistochemistry: suitable | |
| UniProt accession no. | P09038 |
| Biochem/physiol Actions: | The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors.The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human FGF2 |
| Other Notes: | Synthetic peptide located within the following region: RLESNNYNTYRSRKYTSWYVALKRT |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |