Anti-FZD4 antibody produced in rabbit
SIGMA/SAB2108140 - affinity isolated antibody
Product Type: Product-on-demand
Immunohistochemistry Anti-FZD4: Cat. No. SAB2108140: Immunohistochemistry of FZD4 in Skin tissue with FZD4 antibody at 4-8 μg/mL.
Immunoblotting Anti-FZD4: Cat. No.SAB2108140: FZD4 in Fetal Liver tissue lysate with FZD4 antibody at 1.0 μg/mL.
Immunoblotting FZD4 Antibody: Cat. No. SAB2108140: Western Blot analysis of FZD4 in Human Skin cell lysates with FZD4 Antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 60kDa |
| NCBI accession no. | NM_012193   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | bovine, horse, mouse, rat, human, guinea pig |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoblotting: suitable |
| immunohistochemistry: suitable | |
| UniProt accession no. | Q9ULV1 |
| Biochem/physiol Actions: | FZD4 is a member of the frizzled family. Members of this family are seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human FZD4 |
| Other Notes: | Synthetic peptide located within the following region: GITSGMWIWSAKTLHTWQKCSNRLV |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |