Anti-TRPM2 antibody produced in rabbit
SIGMA/SAB2108271 - affinity isolated antibody
Synonym: Anti-EREG1; Anti-KNP3; Anti-LTRPC2; Anti-LTrpC-2; Anti-NUDT9H; Anti-NUDT9L1; Anti-TRPC7
Product Type: Product-on-demand
Immunohistochemistry Immunohistochemistry of TRPM2 in human brain, cortex with TRPM2 antibody at 4-8 μg/mL
Immunohistochemistry Immunohistochemistry of TRPM2 in human heart with TRPM2 antibody at 4-8 μg/mL
Immunoblotting Anti-TRPM2, antibody produced in rabbit: Cat. No. SAB2108271: Immunoblotting analysis of TRPM2 in fetal brain tissue lysate with TRPM2 anitbody at 1 μg/mL.
Western Blotting Western Blot of TRPM2 in Human Fetal Liver with TRPM2 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 171kDa |
| NCBI accession no. | NM_003307   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rat, mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoblotting: suitable |
| immunohistochemistry: suitable | |
| UniProt accession no. | O94759 |
| Biochem/physiol Actions: | TRPM2 is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death.The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human TRPM2 |
| Other Notes: | Synthetic peptide located within the following region: VAILQALLKASRSQDHFGHENWDHQ |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |