Anti-FOXA3
SIGMA/SAB2108468 - affinity isolated antibody
Synonym: Anti- HNF3G; Anti- TCF3G; Anti-FKHH3
Product Type: Product-on-demand
Immunohistochemistry Anti-FOXA3: Cat. No. SAB2108468: Immunohistochemistry of FOXA3 in Human Lung tissue with FOXA3 antibody at 4-8 μg/mL.
Immunoblotting Cell Type: Jurkat (Cat. No. SAB2108468). Lanes 1. Antibody dilution (concentration) 0.5 μg/mL in cell type Jurkat
Western Blotting Western Blot of FOXA3 in Mouse Skeletal Muscle with FOXA3 antibody at 1 μg/mL
| accession no. | NM_004497 |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5-1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 37 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | dog, guinea pig, rat, bovine, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoblotting: suitable |
| immunohistochemistry: suitable | |
| UniProt accession no. | P55318  |
| Biochem/physiol Actions: | Forkhead box A3 (FOXA3) plays a vital role in maintenance of cell glucose homeostasis during prolonged fast. It is also implicated in the regulation of fat mass in humans. FOXA3 inhibits innate immunity and increases the risk of susceptibility to viral infections associated with chronic lung disorders accompanied by chronic goblet cell metaplasia. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Forkhead box A3 (FOXA3), also known as hepatocyte nuclear factor 3 γ (HNF3γ), is encoded by the gene mapped to human chromosome 19q13.32. The encoded protein belongs to the Foxa subfamily. FOXA3 is characterized with a homologous forkhead DNA-binding domain and two transcriptional activation domains located at the N- and C-terminal. |
| Immunogen: | Synthetic peptide directed towards the middle region of human FOXA3 |
| Other Notes: | Synthetic peptide located within the following region: FENGCYLRRQKRFKLEEKVKKGGSG |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |