Anti-HES1
SIGMA/SAB2108472 - IgG fraction of antiserum
Synonym: Anti- HES-1; Anti- HRY; Anti- bHLHb39; Anti-HHL
Product Type: Product-on-demand
Immunohistochemistry Tissue: kidney (Cat. No. SAB2108472). Specification 1. Antibody dilution (concentration) 4-8 μg/mL
Immunohistochemistry HES1 Antibody: Cat. No. SAB2108472: Immunohistochemistry analysis of HES1 in Human Heart with HES1 Antibody Antibody Concentration: 4.0-8.0 μg/mL. Cellular Data: Epithelial cells of renal tubule
Immunoblotting Cell Type: Raji (Cat. No. SAB2108472). Lanes 1. Antibody dilution (concentration) 1.25 μg/mL in cell type Raji
| accession no. | NM_005524 |
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5-1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 30 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | guinea pig, mouse, bovine, horse, human, rabbit, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunofluorescence: suitable |
| immunohistochemistry: suitable | |
| immunoprecipitation (IP): suitable | |
| western blot: suitable | |
| UniProt accession no. | Q14469  |
| Biochem/physiol Actions: | HES1 belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human HES1 |
| Other Notes: | Synthetic peptide located within the following region: NTTPDKPKTASEHRKSSKPIMEKRR |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |