Anti-VDAC1
SIGMA/SAB2108496 - IgG fraction of antiserum
Synonym: Anti- VDAC-1; Anti-PORIN
Product Type: Product-on-demand
Immunohistochemistry Anti-VDAC1: Cat. No. SAB2108496: Immunohistochemistry of VDAC1 in Human Liver tissue with VDAC1 antibody at 4-8 μg/mL.
Immunoblotting Cell Type: HepG2 (Cat. No. SAB2108496). Lanes 1. Antibody dilution (concentration) 1.25 μg/mL in cell type HepG2
Western Blotting Western Blot of VDAC1 in Human with VDAC1 antibody at 1 μg/mL
| accession no. | NM_003374 |
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5-1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 31 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | sheep, human, guinea pig, dog, bovine, rabbit, horse, mouse, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoblotting: suitable |
| immunohistochemistry: suitable | |
| UniProt accession no. | P21796  |
| Biochem/physiol Actions: | The voltage-dependent anion-selective channel 1 (VDAC1) functions as a channel in membranous structures for the outer mitochondrial membrane, the cell membrane, endosomes, caveolae, the sarcoplasmatic reticulum, synaptosomes, and post-synaptic density fraction. A major function of VDAC1 in the plasma membrane is that of a NADH(-ferricyanide) reductase that may be involved in the maintenance of cellular redox homeostasis. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | The previously assigned protein identifier Q5FVE7 has been merged into P21796. Full details can be found on the UniProt database. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human VDAC1 |
| Other Notes: | Synthetic peptide located within the following region: SAKVNNSSLIGLGYTQTLKPGIKLT |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |