Anti-TGFB1
SIGMA/SAB2108514 - affinity isolated antibody
Synonym: Anti- TGF-beta1; Anti- TGFbeta1; Anti- Tgfb-1; Anti-Tgfb
Product Type: Product-on-demand
Immunohistochemistry Anti-TGFB1: Cat. No. SAB2108514: Immunohistochemistry of TGFB1 in Rat and Mouse tissue with TGFB1 antibody at 5-10 μg/mL.
Immunohistochemistry Anti-TGFB1: Cat. No. SAB2108514: Immunohistochemistry of TGFB1 in Human Spleen tissue with TGFB1 antibody at 5.0 μg/mL.
Immunoblotting Cell Type: SP2/0 (Cat. No. SAB2108514). Lanes 1. Antibody dilution (concentration) 1 μg/mL in cell type SP2/0
| accession no. | NM_011577 |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5-1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 43 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoblotting: suitable |
| immunofluorescence: suitable | |
| immunohistochemistry: suitable | |
| UniProt accession no. | P04202  |
| Biochem/physiol Actions: | Tgfb1 is a multifunctional protein that control proliferation, differentiation, and other functions in many cell types. Many cells synthesize TGFB1 and essentially all of them have specific receptors for this protein. It regulates the actions of many other growth factors and determines a positive or negative direction of their effects. It plays an important role in bone remodelling. It is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of mouse TGFB1 |
| Other Notes: | Synthetic peptide located within the following region: DTPEWLSFDVTGVVRQWLNQGDGIQ |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |