Anti-FFAR1
SIGMA/SAB2108661 - affinity isolated antibody
Product Type: Product-on-demand
Immunoblotting Anti-FFAR1: Cat. No. SAB2108661: FFAR1 in Fetal Liver tissue lysate with FFAR1 antibody at 1.0 μg/mL.
| accession no. | NM_005303 |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5-1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 31 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | bovine, human, dog |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoblotting: suitable |
| UniProt accession no. | O14842  |
| Biochem/physiol Actions: | Free fatty acid receptor 1 (FFAR1) is activated by binding of medium or long chain free fatty acids. It increases the Ca2+ level intracellularly through phospholipase C mediated signalling and that potentially stimulates insulin production. FFAR1 is a potential drug target for metabolic diseases like type 2 diabetes. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Free fatty acid receptor 1 (FFAR1) formerly known as G-protein coupled receptor 40 (GPR 40) is predominantly expressed in pancreatic beta cells. In human chromosome, the gene FFAR1 is located on 19q13.12. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human FFAR1 |
| Other Notes: | Synthetic peptide located within the following region: KVSEAALSLLVLILIITSASRSQPK |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |