Anti-FTH1
SIGMA/SAB2108662 - affinity isolated antibody
Synonym: Anti- FTHL6; Anti- MGC104426; Anti- PIG15; Anti- PLIF; Anti-FTH
Product Type: Product-on-demand
Immunohistochemistry Anti-FTH1: Cat. No. SAB2108662: Immunohistochemistry of FTH1 in Kidney tissue with FTH1 antibody at 5.0 μg/mL.
Immunoblotting Anti-FTH1: Cat. No. SAB2108662: FTH1 in Jurkat cell lysate with FTH1 antibody at 1.0 μg/mL.
Western Blotting Western Blot of FTH1 in Human HeLa with FTH1 antibody at 1 μg/mL
Western Blotting Western Blot of FTH1 in Jurkat with FTH1 antibody at 1 μg/mL
Western Blotting Western Blot of FTH1 in Human Ovary Tumor with FTH1 antibody at 1 μg/mL
| accession no. | NM_002032 |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5-1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 21 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | mouse, rabbit, guinea pig, human, dog, horse, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoblotting: suitable |
| immunohistochemistry: suitable | |
| UniProt accession no. | P02794  |
| Biochem/physiol Actions: | FTH1 is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human FTH1 |
| Other Notes: | Synthetic peptide located within the following region: NVNQSLLELHKLATDKNDPHLCDFI |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |