Anti-KRAS
SIGMA/SAB2108685 - affinity isolated antibody
Synonym: Anti- K-RAS2A; Anti- K-RAS2B; Anti- K-RAS4A; Anti- K-RAS4B; Anti-C-K-RAS
Product Type: Product-on-demand
Immunoblotting Anti-KRAS: Cat. No. SAB2108685: KRAS in Fetal Heart tissue lysate with KRAS antibody at 1.0 μg/mL.
Immunoblotting KRAS Antibody: Cat. No. SAB2108685: Western Blot analysis of KRAS in Human Heart cell lysates with KRAS Antibody at 1.0 μg/mL.
Western Blotting Western Blot of KRAS in Human RPMI-8226 with KRAS antibody at 1 μg/mL
Western Blotting Western Blot of KRAS in Human DLD1 Whole Cell with KRAS antibody at 1 μg/mL
Western Blotting Western Blot of KRAS in Human Jurkat Whole Cell with KRAS antibody at 1 μg/mL
Western Blotting Western Blot of KRAS in Mouse Kidney with KRAS antibody at 1 μg/mL
| accession no. | NM_033360 |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5-1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 22 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | mouse, horse, rabbit, guinea pig, rat, yeast, dog, bovine, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoblotting: suitable |
| UniProt accession no. | P01111  |
| Biochem/physiol Actions: | KRAS is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | KRAS is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human KRAS |
| Other Notes: | Synthetic peptide located within the following region: TEYKLVVVGAGGVGKSALTIQLIQN |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |