Anti-TLR2
SIGMA/SAB2108727 - affinity isolated antibody
Synonym: Anti- TIL4; Anti-CD282
Product Type: Product-on-demand
Immunohistochemistry Anti-TLR2: Cat. No. SAB2108727: Immunohistochemistry of TLR2 in pFA fixed Human liver tissue with TLR2 antibody at 4-8 μg/mL.
Immunohistochemistry Anti-TLR2: Cat. No. SAB2108727: Immunohistochemistry of TLR2 in Liver tissue with TLR2 antibody at 5.0 μg/mL.
Immunohistochemistry Anti-TLR2: Cat. No. SAB2108727: Immunohistochemistry of TLR2 in Human lung tissue with TLR2 antibody at 4-8 μg/mL.
Immunohistochemistry Anti-TLR2: Cat. No. SAB2108727: Immunohistochemistry of TLR2 in pFA fixed Human thymus tissue with TLR2 antibody at 4-8 μg/mL.
Immunoblotting Anti-TLR2: Cat. No. SAB2108727: TLR2 in Fetal Brain tissue lysate with TLR2 antibody at 1.0 μg/mL.
Immunoblotting TLR2 Antibody: Cat. No. SAB2108727: Western Blot analysis of TLR2 in Human macrophages cell lysates with TLR2 Antibody at 1.0 μg/mL.
| accession no. | NM_003264 |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5-1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 90 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunofluorescence: suitable |
| immunohistochemistry: suitable | |
| western blot: suitable | |
| UniProt accession no. | O60603  |
| Biochem/physiol Actions: | TLR2 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human TLR2 |
| Other Notes: | Synthetic peptide located within the following region: LEPIEKKAIPQRFCKLRKIMNTKTY |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |