Anti-WNT5A
SIGMA/SAB2108739 - affinity isolated antibody
Synonym: Anti-hWNT5A
Product Type: Product-on-demand
Immunohistochemistry WNT5A Antibody: Cat. No. SAB2108739: Immunohistochemistry analysis of WNT5A in heart with WNT5A Antibody 1.0 μg/mL. Observed Staining: Cytoplasmic,Membrane
Immunohistochemistry Immunohistochemistry of WNT5A in Human Brain with WNT5A antibody at 4-8 μg/mL
Immunohistochemistry Immunohistochemistry of WNT5A in heart with WNT5A antibody at 4-8 μg/mL
Immunoblotting Anti-WNT5A: Cat. No. SAB2108739: WNT5A in HeLa cell lysate with WNT5A antibody at 1.0 μg/mL.
| accession no. | NM_003392 |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5-1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 42 kDa |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | guinea pig, rabbit, mouse, dog, rat, bovine, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoblotting: suitable |
| immunohistochemistry: suitable | |
| UniProt accession no. | P41221  |
| Biochem/physiol Actions: | The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT5A is a member of the WNT protein family. It shows 98%, 98% and 87% amino acid identity to the mouse, rat and the xenopus Wnt5A protein, respectively. The experiments performed in Xenopus laevis embryos identified that human frizzled-5 (hFz5) is the receptor for the Wnt5A ligand and the Wnt5A/hFz5 signaling mediates axis induction.The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98%, 98% and 87% amino acid identity to the mouse, rat and the xenopus Wnt5A protein, respectively. The experiments performed in Xenopus laevis embryos identified that human frizzled-5 (hFz5) is the receptor for the Wnt5A ligand and the Wnt5A/hFz5 signaling mediates axis induction. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human WNT5A |
| Other Notes: | Synthetic peptide located within the following region: GGCGDNIDYGYRFAKEFVDARERER |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |