Anti-APBA1/MINT1 antibody produced in goat
SIGMA/SAB2500073 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-Amyloid-β; Anti-D9S411E; Anti-MINT1
MDL Number: MFCD00803867
Product Type: Chemical
Immunoblotting Anti-APBA1 / MINT1: Cat. No. SAB2500073: (0.1 μg/mL) staining of Human Brain (Cerebellum) lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | goat |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | mouse, human, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: suitable | |
| UniProt accession no. | Q02410  |
| Application: | Anti-APBA1/MINT1 antibody produced in goat is suitable for indirect ELISA and western blot analysis. |
| Biochem/physiol Actions: | APBA1 (Amyloid β (A4) precursor protein binding, family A, member 1) stabilizes amyloid precursor protein (APP) by directly interacting with it. It also restricts production as well as accumulation of proteolytic APP fragment in the brain of Alzheimer′s disease patients. It also suppresses glycogen synthase kinase-3β promoter activity by coupling with a silencer binding protein. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | APBA1 (Amyloid β (A4) precursor protein binding, family A, member 1) is a neuronal adaptor protein belonging to the X11 family. It consists of a centrally located phosphotyrosine binding domain which inhibits the production of Aβ peptide, two C-terminal postsynaptic density-95, large discs, zona occludens 1 (PDZ) domains. |
| Immunogen: | Peptide with sequence C-EASHPSQDGKRQYK from the internal region of the protein sequence according to NP_001154.2. |
| Physical form: | Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 |
| Precautionary statements | P305 + P351 + P338 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |