Anti-ASPORIN/ASPN antibody produced in goat
SIGMA/SAB2500127 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-Asporin (LRR class 1); Anti-FLJ20129; Anti-PLAP1; Anti-SLRR1C
Product Type: Chemical
IImmunofluorescence Anti-Asporin / ASPN: Cat. No. SAB2500127: staining of ATDC5 cells (Panels A and C) and DAPI (panels B and D). Data gratefully received from Dr. Shiro Ikegawa, SNP Research Center, RIKEN, Japan.
Immunoblotting Anti-Asporin / ASPN: Cat. No. SAB2500127: (0.3 μg/mL) staining of Human Bone Marrow lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | goat |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| indirect immunofluorescence: suitable | |
| western blot: suitable | |
| UniProt accession no. | Q9BXN1  |
| Biochem/physiol Actions: | Asporin (ASPN) plays a vital role in regulation of chondrogenesis and helps to maintain the cartilage matrix. ASPN also facilitates transforming growth factor (TGF)-f-mediated signaling. It stimulates osteoblast collagen mineralization by interacting with collagen and calcium. Mutation in the gene is associated with the development of acetabular dysplasia (AD) and hip osteoarthritis. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Asporin (ASPN) is an extracellular matrix (ECM) macromolecule. It is encoded by the gene mapped to human chromosome 9q22.31. ASPN is a member of small leucine-rich proteoglycan (SLRP) family. |
| Immunogen: | Peptide with sequence C-IHENKVKKIQKDT from the internal region of the protein sequence according to NP_060150.3. |
| Physical form: | Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |