Anti-B7-H4 antibody produced in goat
SIGMA/SAB2500141 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-B7S1; Anti-B7X; Anti-B7h.5; Anti-FLJ22418
Product Type: Chemical
Immunoblotting Anti-B7-H4: Cat. No. SAB2500141: (0.3 μg/mL) staining of Human Spleen lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Immunoblotting Anti-B7-H4: Cat. No. SAB2500141: HEK293 overexpressing B7-H4 (RC210360) and probed with Cat. No. SAB2500141 (mock transfection in first lane), tested by Origene.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | goat |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | rat, human, canine, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: suitable | |
| UniProt accession no. | Q7Z7D3  |
| Biochem/physiol Actions: | V-set domain containing T cell activation inhibitor 1 (VTCN1) has a role in T-cell mediated immune responses. It suppresses T-cell action by inhibiting cytokine secretion and the proliferation of cells. VTCN1 has a role in pancreatic cancer and it also promotes tumor immune invasion. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | V-set domain containing T cell activation inhibitor 1 (VTCN1), also known as B7-H4, is a co-stimulating molecule. It is part of the B7 superfamily and the gene encoding it is localized on human chromosome 1p13.1. |
| Immunogen: | Peptide with sequence C-SKGKGNANLEYK from the internal region of the protein sequence according to NP_078902.2. |
| Physical form: | Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |