Anti-FTL antibody produced in goat
SIGMA/SAB2500431 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-Ferritin L subunit; Anti-L apoferritin; Anti-MGC71996
Product Type: Chemical
Immunohistochemistry (4μg/ml) staining of paraffin embedded Human Spleen. Heat induced antigen retrieval with citrate buffer pH 6, HRP-staining.
Immunohistochemistry Negative Control showing staining of paraffin embedded Human Spleen, with no primary antibody.
Western Blotting (0.3μg/ml) staining of Human Brain (Cerebellum) (A), Liver (B), Human Placenta (C)
22kDa in Mouse Brain (D), Rat Brain lysate (35μg protein in RIPA buffer). Detected by chemiluminescence.
22kDa in Mouse Brain (D), Rat Brain lysate (35μg protein in RIPA buffer). Detected by chemiluminescence.
ELISA (1.5ug/ml) as the reporter with EB002025 as the capture rabbit antibody (5ug/ml). This data is from a previous batch, not on sale.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | goat |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | rat, mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| indirect ELISA: suitable | |
| western blot: suitable | |
| UniProt accession no. | P02792  |
| Application: | Anti-FTL antibody produced in goat has been used in western blotting (1:500). |
| Biochem/physiol Actions: | Ferritin light (FTL) subunit is an important protein in iron metabolism but lacks catalytic activity. This protein participates in the nucleation and mineralization of the iron center. FTL acts as a biomarker to differentiate between malignant and benign tumors. Overexpression of the FTL gene is observed in several malignant tumors and plays an important role in mediating the malignancy of cancers. FTL gene plays a role in the pathogenesis of glioblastoma. Mutation or deletion of the FTL gene is associated with neuroferritinopathy. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Ferritin light (FTL) subunit along with ferritin heavy (FTH) subunit are members of the ferritin complex. FTL gene is mapped on the human chromosome at 19q13.33. |
| Immunogen: | Peptide with sequence C-GEYLFERLTLKHD from the C Terminus of the protein sequence according to NP_000137.2. |
| Physical form: | Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |