Anti-GATA1 antibody produced in goat
SIGMA/SAB2500452 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-ERYF1; Anti-GF1; Anti-HGNC:4170; Anti-NFE1
MDL Number: MFCD02096392
Product Type: Chemical
Immunoblotting Anti-GATA1: Cat. No. SAB2500452: (0.3 μg/mL) staining of human PBMC lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | goat |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | human, canine, mouse, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: suitable | |
| UniProt accession no. | P15976  |
| Biochem/physiol Actions: | GATA binding protein 1 (GATA1) plays a crucial role in erythroid and megakaryocyte differentiation and proliferation. It modulates the expression of genes and acts as an E-cadherin repressor. Mutations in the GATA1 gene have been linked to transient abnormal myelopoiesis (TAM) and myeloid leukemia of DS (ML-DS). The protein has anti-apoptotic functions in breast cancer. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | GATA binding protein 1 (GATA1) is a key hematopoietic transcription factor. It is part of the GATA transcription factor family and the gene encoding it is localized on human chromosome Xp11.23. |
| Immunogen: | Peptide with sequence C-DAEAYRHSPVFQ from the internal region of the protein sequence according to NP_002040.1. |
| Physical form: | Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 |
| Precautionary statements | P305 + P351 + P338 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |