Anti-GPX3 antibody produced in goat
SIGMA/SAB2500485 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-Extracellular glutathione peroxidase; Anti-GPx-P; Anti-GSHPx-3; Anti-GSHPx-P; Anti-Glutathione peroxidase 3 (plasma)
Product Type: Chemical
Immunohistochemistry (4μg/ml) staining of paraffin embedded Human Kidney. Heat induced antigen retrieval with citrate buffer pH 6, HRP-staining.
Immunohistochemistry Negative Control showing staining of paraffin embedded Human Kidney, with no primary antibody.
Western Blotting (2μg/ml) staining of Mouse Heart lysate (35μg protein in RIPA buffer). Detected by chemiluminescence.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | goat |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | mouse, canine, rat, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| indirect ELISA: suitable | |
| western blot: suitable | |
| UniProt accession no. | P22352  |
| Application: | Anti-GPX3 antibody has been used in western blotting. |
| Biochem/physiol Actions: | Glutathione peroxidase 3 (GPX3) blocks oxidative damages by decreasing redundant reactive oxygen species (ROS). It plays a major role in solid tumors and hematological malignancies. GPX3 also plays an important role in the effectiveness of leukemic stem cells (LSCs) and self renewal actions of hematopoietic stem cells (HSCs). |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Glutathione peroxidase 3 (GPX3) belongs to the glutathione peroxidase (GPX) family. It is located on human chromosome 5q23. |
| Immunogen: | Peptide with sequence C-NQFGKQEPGENSE from the internal region of the protein sequence according to NP_002075.2. |
| Physical form: | Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |