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Anti-USH1C/Harmonin antibody produced in goat

SIGMA/SAB2501088 - affinity isolated antibody, buffered aqueous solution

Synonym: Anti-AIE-75; Anti-DFNB18; Anti-Harmonin; Anti-PDZ-45; Anti-PDZ-73

Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SAB2501088-100UG 100 µg
$628.00
1/EA
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Immunohistochemistry Anti-USH1C / Harmonin: Cat. No. SAB2501088: (10 μg/mL) staining of paraffin embedded Human Kidney. Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining. (Data have been obtained with Cat. No. SAB2501088 from a previous batch).
Immunoblotting Anti-USH1C / Harmonin: Cat. No. SAB2501088: (0.1 μg/mL) staining of HEK293 lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

antibody form affinity isolated antibody
antibody product type primary antibodies
biological source goat
clone polyclonal
conjugate unconjugated
form buffered aqueous solution
Quality Level 100 
shipped in dry ice
species reactivity mouse, human, rat
storage temp. −20°C
target post-translational modification unmodified
technique(s) immunohistochemistry: suitable
  indirect ELISA: suitable
  western blot: suitable
UniProt accession no. Q9Y6N9 
Biochem/physiol Actions: Harmonin acts as a scaffolding protein and interacts via its six PSD95/Dlg/Z-1 homology (PDZ)-domain with myosin VIIa, scaffold protein containing ankyrin repeats, and SAM domain (SANS), and cadherin 23. It plays a role in normal mechanosensory function in cochlear hair cells. Mutations in the USH1C gene are associated with non-syndromic recessive deafness, retinitis pigmentosa, and Usher syndrome type 1.
Features and Benefits: Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. 
General description: The Usher syndrome type 1C (USH1C) gene encodes for harmonin, a six PSD95/Dlg/Z-1 homology (PDZ) domain-containing protein. The USH1C gene is mapped on the human chromosome at 11p15.1.
Immunogen: Peptide with sequence DRKVAREFRHKVD-C from the N Terminus of the protein sequence according to NP_005700.2; NP_710142.1.
Physical form: Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H315 - H319
Precautionary statements P305 + P351 + P338
RIDADR NONH for all modes of transport
WGK Germany WGK 2
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. −20°C
UNSPSC 12352203

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