Anti-VMAT2/SLC18A2 antibody produced in goat
SIGMA/SAB2501101 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-SLC18A2; Anti-SVAT; Anti-SVMT; Anti-VAT2
MDL Number: MFCD02097601
Product Type: Chemical
Negative Control showing staining of paraffin embedded Human Adrenal Gland, with no primary antibody.
(6μg/ml) staining of paraffin embedded Human Adrenal Gland. Heat induced antigen retrieval with citrate buffer pH 6, HRP-staining.
(2μg/ml) staining of Human Adrenal Gland lysate (35μg protein in RIPA buffer). Detected by chemiluminescence.
Immunohistochemistry (6μg/ml) staining of paraffin embedded Human Adrenal Gland. Heat induced antigen retrieval with citrate buffer pH 6, HRP-staining.
Immunohistochemistry Negative Control showing staining of paraffin embedded Human Adrenal Gland, with no primary antibody.
Western Blotting (2μg/ml) staining of Human Adrenal Gland lysate (35μg protein in RIPA buffer). Detected by chemiluminescence.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | goat |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | rat, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| indirect ELISA: suitable | |
| western blot: suitable | |
| UniProt accession no. | Q05940  |
| Application: | Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Western Blotting (1 paper) |
| Biochem/physiol Actions: | Solute carrier family 18 member A2 (SLC18A2) modulates the release of neurotransmitters like dopamine, serotonin and γ-amino butyric acid. It has a role in the accumulation of neurotransmitters in synaptic vesicles to prevent toxicity. SLC18A2 has been linked to tardive dyskinesia and may be associated with Parkinson’s disease. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Solute carrier family 18 member A2 (SLC18A2) or vesicular monoamine transporter 2 (VMAT2) is a transmembrane protein that acts at nerve terminals. It is expressed in platelets and in central, peripheral and enteric neurons. The gene encoding SLC18A2 consists of 16 exons and is localized on human chromosome 10q25. |
| Immunogen: | Peptide with sequence C-SYPIGEDEESESD from the C Terminus of the protein sequence according to NP_003045.2. |
| Physical form: | Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |