Anti-MYO5A antibody produced in goat
SIGMA/SAB2501441 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-GS1; Anti-MYH12; Anti-MYO5; Anti-MYR12; Myosin VA (heavy chain 12, myoxin)
Product Type: Product-on-demand
Immunofluorescence Anti-MYO5A Cat. No. SAB2501441: (1 μg/mL) staining of Mouse Skeletal Muscle (first panel, and in green in third panel). α-bungaratoxin staining in middle panel and in red in third panel. Detected by fluorescence.
Immunoblotting Anti-MYO5A Cat. No. SAB2501441: (1 μg/mL) staining of Jurkat lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | goat |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | human, pig, bovine, mouse, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: suitable | |
| UniProt accession no. | Q9Y4I1  |
| Biochem/physiol Actions: | Myosin VA associates with the microtubule-based motors and mediates organelle transport. It associates with Ras-related protein Rab-10 and mediates the glucose transporter type 4 translocation to plasma membrane. Mutations in the myosin VA is implicated in hypopigmentation disorder, Griscelli syndrome (GS1) and Elejalde syndrome. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Myosin VA gene is mapped to human chromosome 15q21.2. It is a two-headed actin-based processive motor protein. Myosin VA comprises two heavy chains. Each chain has N-terminal motor domain, a neck region with six light chains and a coiled-coil and globular domain comprising tail region. |
| Immunogen: | Peptide with sequence ETKQLELDLN, from the internal region of the protein sequence according to NP_000250.3; NP_001135967.1 |
| Physical form: | Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin. |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |