Anti-GNB3 antibody produced in goat
SIGMA/SAB2501537 - affinity isolated antibody, buffered aqueous solution
Synonym: G protein, beta-3 subunit; GTP-binding regulatory protein beta-3 chain; Guanine nucleotide binding protein (G protein), beta polypeptide 3; Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 3
Product Type: Product-on-demand
Immunoblotting Anti-GNB3 Cat. No. SAB2501537: (0.1 μg/mL) staining of HepG2 lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | goat |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| indirect ELISA: suitable | |
| western blot: suitable | |
| UniProt accession no. | P16520  |
| Biochem/physiol Actions: | Guanine nucleotide binding protein 3 (GNB3) is involved in the conversion of external receptor activation signals into intracellular signals and it plays an important role in signal transduction pathways. It modulates and associates with favorable antidepressant response. GNB3 takes part in a variety of cellular processes like G protein-coupled receptor signaling. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | The guanine nucleotide binding protein β3 (GNB3) gene is composed of 11 exons and 10 introns. It is the 3 subunit of heterotrimeric G-proteins located on human chromosome 12p13. |
| Immunogen: | Peptide with sequence SGHDNRVSCLGVT, from the internal region of the protein sequence according to NP_002066.1, NP_067642.1 |
| Physical form: | Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin. |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |