Anti-LOR (N-terminal) antibody produced in rabbit
SIGMA/SAB2701259 - affinity isolated antibody, buffered aqueous solution
Synonym: LOR; MGC111513
Product Type: Product-on-demand
Immunohistochemistry Loricrin antibody [N1], N-term detects LOR protein at cytosol on HBL438 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded HBL438 xenograft. Loricrin antibody [N1], N-term (SAB2701259) dilution: 1:500.
Immunofluorescence Immunofluorescence analysis of methanol-fixed Hep3B, using Loricrin(SAB2701259) antibody at 1:500 dilution.
Western Blotting Whole cell extract (30 μg) was separated by 12% SDS-PAGE, and the membrane was blotted with Loricrin antibody [N1], N-term (SAB2701259) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Western Blotting Sample (30 μg of whole cell lysate) A: Raji 12% SDS PAGE SAB2701259 diluted at 1:1000 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NP_000418   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:1000 |
| indirect immunofluorescence: suitable | |
| western blot: 500-3000 | |
| UniProt accession no. | P23490 |
| Application: | Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IHC-P: 1:100-1:1000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
| Biochem/physiol Actions: | This gene encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel′s syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases. [provided by RefSeq] |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Immunogen: | Synthetic peptide corresponding to a region within amino acids 1 and 46 of Loricrin according to NP_000418 |
| Physical form: | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H317 - H412 |
| Precautionary statements | P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |