Anti-NTSR1 antibody produced in rabbit
SIGMA/SAB2900692 - affinity isolated antibody
Synonym: NT-1r; NT1 receptor; NTR; NTS1; NTSR1; Neurotensin receptor type 1
Product Type: Product-on-demand
Immunohistochemistry Anti-NTSR1 (C-Terminus), antibody produced in rabbit: Cat. No. SAB2900692: Anti-NTSR1 antibody IHC staining of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: 6 μg/mL |
| UniProt accession no. | P30989  |
| Application: | Anti-NTSR1 antibody produced in rabbit has been used in immunohistochemistry (IHC) (1:500). |
| Biochem/physiol Actions: | The neurotensin receptor 1 (NTSR1) plays a regulatory role in the initiation, proliferation, apoptosis, metastasis, and differentiation of tumors through several pathways. Overexpression of NTSR1 is seen in lung cancer, malignant prostatic tumors, and malignant cell lines. NTSR1 is a risk factor that participates in the progression of ductal breast cancer. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | The neurotensin receptor 1 (NTSR1) gene has 4 exons and 3 introns and is 53.93 Kb long. NTSR1 is a member of the G protein-coupled receptor (GPCR) family. It consists of 4 extracellular and intracellular loops. It is expressed in the amygdal nucleus, ventral tegmental area, substantia nigra, striatum and entorhinal, and prefrontal cortices of the central nervous system. |
| Immunogen: | Synthetic 18 amino acid peptide from N-terminal extracellular domain of human NTSR1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Elephant (94%); Marmoset (89%); Hamster (83%). |
| Physical form: | Solution in phosphate-buffered saline containing less than 0.1% sodium azide. |
| Physical form: | Supplied at 1 mg/ml |
| Hazard Codes | Xn |
| Risk Statements | 21/22 |
| Safety Statements | 36/37 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |