Anti-ADCYAP1R1 antibody produced in rabbit
SIGMA/SAB2900695 - affinity isolated antibody
Synonym: ADCYAP1R1; PAC1; PAC1-R; PACAP receptor 1; Pac1 receptor; Pac1 receptors
Product Type: Product-on-demand
Immunohistochemistry Anti-ADCYAP1R1 (N-Terminus), antibody produced in rabbit: Cat. No. SAB2900695: Anti-ADCYAP1R1 antibody IHC staining of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | dog, human, Xenopus, chicken, monkey |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: 15 μg/mL |
| UniProt accession no. | P41586  |
| Biochem/physiol Actions: | Adenylate cyclase activating polypeptide 1 (pituitary) receptor type I (ADCYAP1R1) or pituitary adenylate cyclase 1 receptor (PAC1R) protein can activate the adenylyl cyclase stimulatory G protein Gs. It regulates circadian rhythm, food intake, and the immune system. PAC1R plays a vital role in glucose metabolism, learning and memory, neuronal ontogenesis, and apoptosis. ADCYAP1R1 is identified as a potential drug target for mental disorders and dry eye syndrome. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Adenylate cyclase activating polypeptide 1 (pituitary) receptor type I (ADCYAP1R1) or pituitary adenylate cyclase 1 receptor (PAC1R) protein is a member of the class B G-protein-coupled receptors (GPCRs). It is expressed ubiquitously in the central nervous system (CNS) and peripheral tissues. It has an N-terminal extracellular domain (ECD) and a transmembrane domain (TMD). ADCYAP1R1 gene is located on human chromosome 7p14. |
| Immunogen: | Synthetic 17 amino acid peptide from C-terminus of human ADCYAP1R1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Panda, Dog, Bat, Chicken, Lizard, Xenopus (100%); Stickleback, Pufferfish, Zebrafish (94%); Mouse, Rat, Hamster, Elephant, Bovine, Horse, Pig (88%). |
| Physical form: | Solution in phosphate-buffered saline containing less than 0.1% sodium azide. |
| Physical form: | Supplied at 1 mg/ml |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |