Anti-LRFN1 antibody produced in rabbit
SIGMA/SAB3500014 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-Leucine-rich repeat and fibronectin typeIII domain-containing protein 1; Anti-Synaptic adhesion-like molecule 2
Product Type: Chemical
Immunohistochemistry Anti-LRFN1: Cat. No. SAB3500014: LRFN1 in mouse brain tissue with LRFN1 antibody at 2.5 μg/mL.
Immunofluorescence Immunofluorescence of LRFN1 in mouse brain tissue with LRFN1 antibody at 20 μg/mL.
Immunoblotting Anti-LRFN1: Cat. No. SAB3500014: LRFN1 in human brain lysate with LRFN1 antibody at (A) 1 and (B) 2 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | Q9P244   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human, mouse, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunofluorescence: suitable |
| immunohistochemistry: suitable | |
| indirect ELISA: suitable | |
| western blot: suitable | |
| UniProt accession no. | Q9P244 |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | LRFN1 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN1 are known to exist. This antibody is predicted to not cross-react with other members of the LRFN family. |
| Immunogen: | LRFN1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human LRFN1. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP3500014 . |
| Physical form: | Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |