Anti-MATN1 antibody produced in rabbit
SIGMA/SAB3500034 - affinity isolated antibody, buffered aqueous solution, ab1
Synonym: Anti-CMP; Anti-CRTM; Anti-Cartilage matrix protein; Anti-Matrilin 1
Product Type: Chemical
Immunohistochemistry Anti-MATN1: Cat. No. SAB3500034: MATN1 in human liver tissue with MATN1 antibody at 5 μg/mL.
Immunofluorescence Immunofluorescence of MATN1 in Human Liver cells with MATN1 antibody at 20 μg/mL.
Immunoblotting Anti-MATN1: Cat. No. SAB3500034: MATN1 in rat liver tissue lysate with MATN1 antibody at (A) 1 and (B) 2 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NP_002370   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | mouse, rat, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunofluorescence: suitable |
| immunohistochemistry: suitable | |
| indirect ELISA: suitable | |
| western blot: suitable | |
| UniProt accession no. | P21941 |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN1 is composed of two Willebrand Factor A (vWFA) domains separated by one EGF-like domain, whereas MATN3 is composed of a single N-terminal vWFA domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that the MATN1 promoter region was associated with both susceptibility and disease progression in Adolescent idiopathic scoliosis. |
| Immunogen: | MATN1 antibody was raised against a 13 amino acid peptide from near the carboxy terminus of human MATN1. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP3500034 . |
| Physical form: | Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |