Anti-SCARB1 antibody produced in rabbit
SIGMA/SAB3500048 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-CD36 and LIMPII analog; Anti-CD36 antigen-like 1; Anti-CLA-1; Anti-SR-BI; Anti-SRB1; Anti-Scavenger receptor class B member 1
MDL Number: MFCD01634166
Product Type: Chemical
Immunohistochemistry Anti-SCARB1: Cat. No. SAB3500048: SCARB1 in human spleen tissue with SCARB1 antibody at 2.5 μg/mL.
Immunofluorescence Immunofluorescence of SCARB1 in Human Spleen tissue with SCARB1 antibody at 20 μg/mL.
Immunoblotting Anti-SCARB1: Cat. No. SAB3500048: SCARB1 in human spleen tissue lysate with SCARB1 antibody at (A) 1 and (B) 2 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | Q8WTV0   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human, mouse, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: suitable |
| immunofluorescence: suitable | |
| immunohistochemistry: suitable | |
| western blot: suitable | |
| UniProt accession no. | Q8WTV0 |
| Application: | Anti-SCARB1 antibody produced in rabbit has been used for immunohistochemistry. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Scavenger receptor class B member 1 (SCARB1), also known as SR-BI, is part of the scavenger receptor superfamily, which is composed of many members with diverse structures, expression patterns, and functions. SCARB1 is a multi-ligand cell-surface receptor that mediates the selective uptake of lipid from HDL cholesterol into cells and is expressed in steroidogenic tissues in adult animals. Other ligands of SCARB1 include native, acetylated, or oxidized LDL and anionic phospholipids. SCARB1-deficient mice have elevated HDL levels and increased susceptibility to atherosclerosis on fat feeding, indicating its importance in the regulation of cholesterol homeostasis. Along with CLDN1, LDL-R, and the tetraspanin superfamily member CD81, SCARB1 has been reported to be an entry factor for the Hepatitis C virus. At least two isoforms of SCARB1 are known to exist. |
| Immunogen: | SCARB1 antibody was raised against a 15 amino acid peptide near the amino terminus of human SCARB1. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP3500048 . |
| Physical form: | Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |