Anti-Swine H1N1 Hemagglutinin antibody produced in rabbit
SIGMA/SAB3500061 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-HA; Anti-S-OIV A Hemagglutinin; Anti-Swine flu H1; Anti-Swine-Origin Influenza A (H1N1) Hemagglutinin
MDL Number: MFCD00803873
Product Type: Chemical
ELISA Anti-Swine H1N1 Hemagglutinin: Cat. No. SAB3500061: Anti-Swine-origin Hemagglutinin antibody at 2 μg/mL specifically recognizes swine-origin influenza virus (S-OIV) A H1N1 but not seasonal influenza virus A H1N1 Hemagglutinin protein.
ELISA Anti-Swine H1N1 Hemagglutinin: Cat. No. SAB3500061: Anti-Swine H1N1 Hemagglutinin antibody at 1 μg/mL and the blocking and corresponding peptides at 50, 10, 2 and 0 ng/mL.
Immunoblotting Anti-Swine H1N1 Hemagglutinin: Cat. No. SAB3500061: Hemaggutinin using recombinant seasonal Hemagglutinin (lanes A and B) and swine-origin Hemagglutinin (lanes C and D) with anti-seasonal Hemagglutinin antibody (5235) at 2 μg/mL (lanes A and C) and anti-swine-origin Hemagglutinin antibody (5237) at 2 μg/mL (lanes B and D).
ELISA ELISA results using Swine H1N1 Hemagglutinin antibody at 1 μg/mL and the blocking and corresponding peptides at 50, 10, 2 and 0 ng/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | ACQ76314   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | viral |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: suitable | |
| UniProt accession no. | C4AL34 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA (1). In early 2009, a novel swine-origin influenza A (H1N1) virus was identified in specimens obtained from patients in Mexico and the United States (2). The virus spread quickly around the world and on June 11, 2009, the World Health Organization declared it a pandemic (3). Influenza A virus has one of sixteen possible Hemagglutinin (HA) surface proteins and one of nine possible Neuraminidase (NA) surface proteins. The Hemagglutinin protein facilitates viral attachment while Neuraminidase is involved in viral release. These proteins also elicit immune responses that prevent infection or independently reduce viral replication. The genetic make-up of this swine flu virus is unlike any other: it is an H1N1 strain that combines a triple assortment first identified in 1998 including human, swine, and avian influenza with two new pig H3N2 virus genes from Eurasia, themselves of recent human origin (4). The distinct antigenic properties of the new swine virus compared with seasonal influenza A (H1N1) virus suggest that human immunity against new swine influenza virus is limited, although the age distribution of reported cases suggests some degree of protection in older age groups (5). This antibody is specific for the novel swine influenza Hemagglutinin and will not recognize the corresponding Hemagglutinin sequence from the seasonal H1N1 influenza (A/Brisbane/59/2007 (H1N1)). |
| Immunogen: | Hemagglutinin antibody was raised against a synthetic peptide from the novel swine influenza Hemagglutinin protein. The peptide sequence is unique from the peptide sequence for product SAB3500063 and SAB3500059. This antibody is a cognate pair with product SAB3500060. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP3500061 . |
| Physical form: | Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |