Anti-TWA1 antibody produced in rabbit
SIGMA/SAB3500088 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-Two hybrid-associated protein 1 with RanBPM
Product Type: Chemical
Immunohistochemistry Immunohistochemistry of TWA1 in rat brain tissue with TWA1 antibody at 2.5 μg/mL.
Immunoblotting Anti-TWA1: Cat. No. SAB3500088: TWA1 in human brain tissue lysate with TWA1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NP_060366   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | mouse, rat, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunofluorescence: suitable |
| immunohistochemistry: suitable | |
| indirect ELISA: suitable | |
| western blot: suitable | |
| UniProt accession no. | Q9NWU2 |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | TWA1 was identified through a two hybrid-associated protein screen with RanBPM. TWA1 is well conserved through evolution and is localized within the nucleus. It interacts with RanBP9 and comprises a protein complex with RanBPM and Muskelin. TWA1 was found to possess the LisH-CTLH motif which is detected in proteins involved in microtubule dynamics, cell migration, nucleokinesis and chromosome segregation. These functions overlap with functions suggested for the RanGTPase cycle. Recent findings suggested that there is an as yet uncovered function of the RanGTPase cycle. |
| Immunogen: | TWA1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human TWA1. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP3500088 . |
| Physical form: | Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |